Generic vs Branded Medicines: What’s the Difference?

When you collect a prescription, you may be offered a generic medicine instead of a branded one. Many patients wonder whether generic medicines are as effective or safe. The short answer is yes — but understanding the difference can help you make informed choices.

What is a branded medicine?
A branded medicine is the original product developed by a pharmaceutical company. It is sold under a brand name and is protected by a patent for a period of time. During this time, only the original manufacturer may produce and sell it.

What is a generic medicine?
Once the patent expires, other manufacturers are allowed to produce the same medicine. These versions are known as generics. They contain the same active ingredient, in the same strength, and work in the same way as the branded medicine.

Are generic medicines safe?
Yes. In South Africa, generic medicines are regulated and approved by the relevant authorities. They must meet strict standards for quality, safety and effectiveness before they are allowed onto the market.

Why are generic medicines usually cheaper?
Generic manufacturers do not carry the original research and development costs. As a result, generics are often more affordable, making long-term treatment more accessible for many patients.

Will a generic medicine work the same way?
For most people, yes. Generic medicines are designed to work in the same way as branded versions. In some cases, inactive ingredients such as colourings or fillers may differ slightly, but these do not affect how the medicine treats the condition.

When should I speak to a pharmacist?
If you have concerns, experience side effects, or are unsure about switching between branded and generic medicines, speak to your pharmacist. They can explain your options and help you choose what’s most suitable for you.

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